See all posts by James J. McCombie The Tiziana Life Sciences (LSE:TILS) share price is up 228% over 12 months. But, Tiziana stock is also down 38% from its July 2020 all-time high. Those numbers reflect the wild ride that Tiziana shareholders have been on in 2020 and into 2021. Enter Your Email Address Image source: Getty Images. The high-calibre small-cap stock flying under the City’s radar Renowned stock-picker Mark Rogers and his analyst team at The Motley Fool UK have named 6 shares that they believe UK investors should consider buying NOW.So if you’re looking for more stock ideas to try and best position your portfolio today, then it might be a good day for you. Because we’re offering a full 33% off your first year of membership to our flagship share-tipping service, backed by our ‘no quibbles’ 30-day subscription fee refund guarantee. Adventurous investors like you won’t want to miss out on what could be a truly astonishing opportunity…You see, over the past three years, this AIM-listed company has been quietly powering ahead… rewarding its shareholders with generous share price growth thanks to a carefully orchestrated ‘buy and build’ strategy.And with a first-class management team at the helm, a proven, well-executed business model, plus market-leading positions in high-margin, niche products… our analysts believe there’s still plenty more potential growth in the pipeline.Here’s your chance to discover exactly what has got our Motley Fool UK investment team all hot-under-the-collar about this tiny £350+ million enterprise… inside a specially prepared free investment report.But here’s the really exciting part… right now, we believe many UK investors have quite simply never heard of this company before! Tiziana is a pharmaceutical company whose stated mission is to develop innovative drugs to treat Crohn’s disease, progressive multiple sclerosis, and hepatocellular carcinoma. On 10 March 2020, Tiziana announced it was investigating a potential treatment for patients with Covid-19, and in April 2020, Tiziana filed a couple of patents for Covid-19 treatments. This seems to have been the catalyst for Tiziana’s stock price action from 2020 to 2021.5G is here – and shares of this ‘sleeping giant’ could be a great way for you to potentially profit!According to one leading industry firm, the 5G boom could create a global industry worth US$12.3 TRILLION out of thin air…And if you click here we’ll show you something that could be key to unlocking 5G’s full potential…Covid-19 treatmentThe Tiziana share price fell from 265p to 75p in December 2020. Then it climbed to around 195p in mid-January, before falling back to around 100p now. I think that as public concern about the pandemic waned over the latter half of 2020, so did investor interest in Tiziana. When daily coronavirus infections started to rise in winter 2020, culminating in a national lockdown, the Tiziana share price rose again. It has fallen since mid-January which coincides with timelines for emerging from lockdown being released and the vaccination programme in the UK gathering pace. However, it is also worth mentioning that Tiziana graduated from the AIM market and moved onto the London Stock Exchange‘s main market on 20 January 2020.Tiziana’s so far un-approved antibody-based treatments for Covid-19 might not be if the coronavirus pandemic ends. A similar treatment produced by a rival company is already approved for use against Covid-19, and perhaps investors fear that this will mop up all available demand. If investors are thinking along these lines, I believe they are missing something about the Tiziana share price prospects.Tiziana product pipelineTiziana is not selling any drugs at present and thus does not report revenue so continuing fund raises will be necessary. It does have three compounds in various stages of development for multiple indications. No phase 3 trials — typically the last stage to complete before approval for marketing a drug can be considered — have been started as yet. Tiziana is probably still years away from selling a drug, but it does have another potential path to profit.Tiziana Life Sciences PipelineSource: Tiziana Life Sciences Investor PresentationTiziana has a revolutionary platform technology that enables oral, nasal, and inhaled administration of monoclonal antibodies. These typically need to be given by an IV infusion which is tough to do in the community. Tiziana, if successful, could bring treatments to market that can be picked up from a local pharmacy. That really would be a game-changer. Tiziana could get royalty income from other drugs companies by licensing this technology in addition to using it itself.Tiziana share priceEarly-stage pharma companies are always risky. Depending on the source, up to 90% of drugs don’t make it from phase 1 trials to market. I would not buy Tiziana shares at the moment. The company’s value is bound to its platform and the two drugs being investigated for delivery using it. I would rather wait until I see some phase 2 trial data to make a decision.However, I do think the success or failure of the potential Covid-19 treatment is being over-emphasised. Treatments for Covid-19 will be required for some time yet. Also, the treatment has applications beyond Covid-19. James J. McCombie has no position in any of the shares mentioned. The Motley Fool UK has no position in any of the shares mentioned. Views expressed on the companies mentioned in this article are those of the writer and therefore may differ from the official recommendations we make in our subscription services such as Share Advisor, Hidden Winners and Pro. Here at The Motley Fool we believe that considering a diverse range of insights makes us better investors. I would like to receive emails from you about product information and offers from The Fool and its business partners. Each of these emails will provide a link to unsubscribe from future emails. More information about how The Fool collects, stores, and handles personal data is available in its Privacy Statement. Simply click below to discover how you can take advantage of this. Click here to claim your copy of this special investment report — and we’ll tell you the name of this Top Small-Cap Stock… free of charge! Our 6 ‘Best Buys Now’ Shares Is Tiziana Life Sciences stock a buy? James J. McCombie | Monday, 29th March, 2021 | More on: TILS
“The first thing with a captain is that he has to be one of the first players selected. You’ve got to know the guy is going to be in the team. Secondly, whatever values we have in the team, they have to live those values so that every time a player looks at that captain they know the values that are important for the team, he’s leading the way.“Those stories about Richie McCaw are true. In training they go from one drill to the next and he sprints there, he’s the first there. He cleans the changing room after the game, that’s the sort of guy you want. But it’s not just one guy, you need a group of players around him to support him. I’m sure those players are in England, we just have to find them. Leadership is something you have to develop.” Team leaders? Dylan Hartley and Chris Robshaw during anthems LATEST RUGBY WORLD MAGAZINE SUBSCRIPTION DEALS So which of these fellas do you think should captain England into the Six Nations? Remember this is the top five according to the bookies – perhaps none of these men should be leaders in the new-look England side. Let us know what you think by voting! Who should captain England during the Six Nations? (Poll Closed) None of the above 32.17% Joe Launchbury 26.65% Dylan Hartley 12.83% Chris Robshaw 12.75% Tom Wood 11.82% Owen Farrell 3.77% Create Your Own Poll Who should captain England during the Six Nations? With Eddie Jones taking over as the head coach of England, there are sure to be some big changes at Twickenham. Chiefly amongst them, many believe, is with his choice of captain.During the World Cup, Jones had said in a newspaper column that Chris Robshaw was “not outstandingly good in any area”. However, in a U-turn during his unveling, Jones claimed he was being a “bit naughty” and that he would seek to sit down with Robshaw and talk things through with the incumbent captain.Explaining his position now, Jones said: “One of the first things I have to do is sit down with Chris and chat to him. I’ve watched a couple of his games since the World Cup and, as with all the players, he’s starting from zero. There’s always an opportunity to change things and he’s in that position. He’s got a nice cafe in Winchester. Fantastic coffee. Best coffee in England. I might grab him for a coffee down there.”Clean slate: Eddie Jones in his first appearance at TwickenhamDespite these comments, the bookies have installed Wasps lock Joe Launchbury as the favourite to lead England into the Six Nations, with Robshaw second favourite. Jones did further explain what he expects from a captain.
ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/271545/mandai-courtyard-house-atelier-ma Clipboard Projects “COPY” Mandai Courtyard House / Atelier M+ASave this projectSaveMandai Courtyard House / Atelier M+A Photographs: Robert SuchProject Team:Masaki Harimoto, Ng Ai Hwa, Wang Mei YeeCountry:SingaporeMore SpecsLess SpecsText description provided by the architects. Setting amidst the nature reserve that bounds the Upper Seletar reservoir, the bungalow at Mandai area is bestowed with the serenity and repose rarely found in the island of buzzling Singapore.Save this picture!© Robert SuchRecommended ProductsWindowsOTTOSTUMM | MOGSWindow Systems – BronzoFinestra B40WindowsJansenWindows – Janisol PrimoWindowsAir-LuxSliding Window – CurvedEnclosures / Double Skin FacadesIsland Exterior FabricatorsCurtain Wall Facade SystemsIn the island where every inch of land is dear, the owner’s brief for a single-storey bungalow house is unusual, and reflects a nonchalant attitude towards the mainstream practice of maximising the allowable buildable area granted by the authority.Save this picture!© Robert SuchThe house is designed in an orthogonal ‘doughnut’ shape, with the interior spaces surrounding a central open courtyard. The ‘doughnut’ configuration allows the owner to enjoy a secured outdoor space inside the building during the evenings after work, while the roof laid with timber deck above the living/dining space is an ‘outdoor living/dining space’ during parties and gathering.Save this picture!© Robert SuchThe living/dining space make up the front of the house that opens up to the road along the front boundary. A wall-to-wall timber deck strip aligns each side of the living/dining space where one could sit to enjoy the front garden and the courtyard, not unlike the ‘engawa’ concept of the traditional Japanese house, which is a transitory space between the ‘inside’ and the ‘outside’. Full-height glass sliding panels open the interior and the central courtyard to the public unapprehensively to blend the exterior into the interior. Natural light abounds the interior and constant breeze of fresh air is a given for the abode.Save this picture!© Robert SuchAn overhanging canopy floats in front of the entrance door to create a weightless statement in contrast to the grounded house form. The white colour with black colour such as ‘gargoyles’ and window frames as accentuation is a tribute towards the black and white colonial bungalows which are significant in Singapore.Save this picture!First Floor PlanProject gallerySee allShow lessmodeLab Data LabArticlesmodeLab Grasshopper WebinarArticles Share “COPY” Mandai Courtyard House / Atelier M+A 2011 Singapore CopyHouses•Singapore Year: Architects: Atelier M+A Area Area of this architecture project Area: 572 m² Year Completion year of this architecture project ArchDaily Houses ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/271545/mandai-courtyard-house-atelier-ma Clipboard Save this picture!© Robert Such+ 23 Share Photographs CopyAbout this officeAtelier M+AOfficeFollowProductsWoodGlassConcrete#TagsProjectsBuilt ProjectsSelected ProjectsResidential ArchitectureHousesWoodHousesSingaporePublished on September 19, 2012Cite: “Mandai Courtyard House / Atelier M+A” 19 Sep 2012. ArchDaily. Accessed 11 Jun 2021.
Architect In Charge:APOLLO Architects & Associates, Satoshi KurosakiCity:Setagaya CityCountry:JapanMore SpecsLess SpecsSave this picture!© Masao NishikawaRecommended ProductsMetallicsStudcoWall Stop Ends – EzyCapMetallicsSculptformClick-on Battens in Ivanhoe ApartmentsEnclosures / Double Skin FacadesAlucoilStructural Honeycomb Panels – LarcoreWindowsSolarluxSliding Window – CeroText description provided by the architects. A two-family house situated in a residential Tokyo neighborhood. While the living areas are completely separate, the construction features a rhythmically and holistically integrated façade that suits the characteristics of each household. By providing the parental household (consisting of two parents and a daughter) with a first-floor living-dining kitchen and placing cedar-textured bare concrete walls on the road side, this residence functions as a courtyard house that connects to the forecourt on the entrance side while ensuring privacy.Save this picture!© Masao NishikawaSave this picture!© Masao NishikawaSave this picture!Ground and first floor plansSave this picture!© Masao NishikawaAlso, the private floors on the second and third stories incorporate separate private rooms that give each adult resident the freedom to live independently. Meanwhile, the child household features a central courtyard that creates a separation between the front and inner spaces, linked by a bridge on the second floor. On the first floor, the bathroom and the bedrooms face each other across the courtyard, enhancing privacy.Save this picture!© Masao NishikawaIn addition, because the second floor is a high-ceiling atrium, natural light from high windows and skylights fills the room to create a roomy spaciousness. Because the bridge on the second floor is outside, the living room and dining kitchen are functionally separated into a “main building” and “annex,” facilitating life together while ensuring privacy.It is almost like an urban resort that evokes the atmosphere of a private villa. At night, the minimal space illuminated by indirect lighting is joined by a warm impression, making you forget that this is a residential area.Save this picture!© Masao NishikawaProject gallerySee allShow lessThe Rose of Vierschach / Pedevilla ArchitectsSelected ProjectsJump Hub / Jakub Cigler Architekti + Unlimited Jakub Cigler ArchitektiSelected Projects Share Projects Photographs: Masao Nishikawa RHYTHM House / APOLLO Architects & AssociatesSave this projectSaveRHYTHM House / APOLLO Architects & Associates Houses CopyHouses•Setagaya City, Japan Structural Engineer: ArchDaily “COPY” RHYTHM House / APOLLO Architects & Associates Architects: APOLLO Architects & Associates Area Area of this architecture project SIRIUS LIGHTING OFFICE Japan 2018 Save this picture!© Masao Nishikawa+ 33Curated by Hana Abdel Share “COPY” Photographs Area: 179 m² Year Completion year of this architecture project Masaki Structures Lighting Design: ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/933555/rhythm-house-apollo-architects-and-associates Clipboard Year: ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/933555/rhythm-house-apollo-architects-and-associates Clipboard CopyAbout this officeAPOLLO Architects & AssociatesOfficeFollow#TagsProjectsBuilt ProjectsSelected ProjectsResidential ArchitectureHousesSetagaya CityOn FacebookJapanPublished on February 13, 2020Cite: “RHYTHM House / APOLLO Architects & Associates” 12 Feb 2020. ArchDaily. Accessed 10 Jun 2021.
YMCA England is planning a new set of direct marketing initiatives ranging from new donor recruitment to cultivation as part of the development of its marketing programme. YMCA England’s Direct Marketing Manager Catherine Lawson said: “YMCA England has a really difficult task of communicating the important work we do in local communities in a simple and compelling way. We need to test and define our core proposition to establish the strongest direct marketing messages to raise income. Domain is committed to helping us achieve this objective.”Over 150 YMCAs around the country will benefit from this work. The agency will produce its first work for YMCA England in late autumn, on a homelessness appeal. Advertisement YMCA England plans direct marketing initiative with The Domain Group About Howard Lake Howard Lake is a digital fundraising entrepreneur. Publisher of UK Fundraising, the world’s first web resource for professional fundraisers, since 1994. Trainer and consultant in digital fundraising. Founder of Fundraising Camp and co-founder of GoodJobs.org.uk. Researching massive growth in giving. Howard Lake | 18 September 2002 | News AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis 14 total views, 1 views today AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis
UK Fundraising has found a home for its unwanted Dell 17″ monitor using the donateapc.org.uk Web site.The recent purchase of a new monitor at UK Fundraising means we had a spare Dell 17″ monitor which was still in good condition and needed to find a good home.We used the free services of donateapc.org.uk to announce its availability and this morning a local charity picked it up to take to their office. Advertisement About Howard Lake Howard Lake is a digital fundraising entrepreneur. Publisher of UK Fundraising, the world’s first web resource for professional fundraisers, since 1994. Trainer and consultant in digital fundraising. Founder of Fundraising Camp and co-founder of GoodJobs.org.uk. Researching massive growth in giving. The donateapc.org.uk site worked very well. It was easy to post details of the monitor, and we received requests for it from three organisations, so the site clearly gets used well. After the charity picked up the monitor we were able to return to the Web site and delete the monitor from the listing, without any complicated user IDs or passwords to remember.There are a number of PC and hardware recycling sites online, but donateapc.org.uk was set up specifically to cater for the individuals and companies who only had one or two bits of kit to donate. Most of the other sites catered for larger companies who wanted to donate many items in one go.All in all it proved a very effective and easy-to-use service. UK Fundraising donates monitor via donateapc.org.uk Tagged with: Consulting & Agencies Technology Trading Howard Lake | 11 February 2004 | News 22 total views, 1 views today AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis
Tagged with: Funding About Howard Lake Howard Lake is a digital fundraising entrepreneur. Publisher of UK Fundraising, the world’s first web resource for professional fundraisers, since 1994. Trainer and consultant in digital fundraising. Founder of Fundraising Camp and co-founder of GoodJobs.org.uk. Researching massive growth in giving. 21 total views, 1 views today AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis A Guide to Grants for Individuals in Need 2009-2010 2009-2010 Howard Lake | 26 June 2009 | News AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis
IoF shares recent experiences of UK fundraisers at international conference Tagged with: Institute of Fundraising Law / policy Rogare AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis4 133 total views, 1 views today Howard Lake | 3 May 2017 | News Advertisement Photo: Jason Lee (interim President and CEO of AFP) , Peter Lewis (CEO of Institute of Fundraising), Leah Eustace (President, Your Blue Canoe) and Emmett Carson (CEO, Silicon Valley Community Foundation). 134 total views, 2 views today AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis4 Peter Lewis, Chief Executive of the Institute of Fundraising, encouraged fundraisers from around the world to ‘place donors at the heart of your fundraising’.Lewis was speaking in front of an international fundraising audience at the Association of Fundraising Professionals’ annual conference in the USA.He was one of three guests speaking at Tuesday’s General Session at the AFP conference which focused on the public policy and media landscape across the United States, Canada and the UK. He shared the experiences of the Institute and of charities over the pasts two years, during which media and political attention has focused on some fundraising practices carried out by some charities and their agencies.He explained how these had led to a new regulatory regime, and how this had taken places amid reports of a drop in the levels of the public’s trust in charities.At AFP he explained how charities can best respond and energise their supporters and donors.In his opening remarks, he also emphasised the importance of ensuring a charity’s values are embedded within their fundraising practice.Ian MacQuillin, Director of Rogare, presented his analysis of and lessons from the media attacks on fundraising in a session at AFP on “Why Media Attacks on Fundraising Really Are ‘Ideological’ and How We Can Deal With Them”.The AFP International Fundraising Conference is held each spring and brings more than 4,000 fundraising professionals together to discuss, teach, and learn about new development issues.This year it took place in San Francisco from 30 April to 2 May. About Howard Lake Howard Lake is a digital fundraising entrepreneur. Publisher of UK Fundraising, the world’s first web resource for professional fundraisers, since 1994. Trainer and consultant in digital fundraising. Founder of Fundraising Camp and co-founder of GoodJobs.org.uk. Researching massive growth in giving.
Twitter Pinterest Twitter WhatsApp Pinterest WhatsApp Facebook Alton Coursey A 32-year-old man was arrested Wednesday after he reportedly punched, choked and sexually assaulted his ex-girlfriend. Alton Ray Coursey was charged with sexual assault, a second-degree felony, and assault impeding breathing and circulation (family violence), third-degree felony. The 30-year-old woman stated she was physically and sexually assaulted at 12:30 a.m. June 8 in the 10000 block of West Bradley Drive, an Ector County Sheriff’s Office affidavit detailed. The woman reportedly took her husband to work at 12:01 a.m. and then went to hang out with friends at Big Daddy Zane’s located at 6840 W. University Blvd. While the woman was at the bar, she ran into her ex-boyfriend and they began to argue, the affidavit stated. The woman stated to avoid conflict she began walking to her vehicle in an attempt to leave. Coursey reportedly followed her out to her vehicle, took her keys and made her get into the vehicle and then they left the parking lot. The woman stated while in the alley of Big Daddy Zane’s that Coursey placed the vehicle in park and began to physically assault her. The woman stated Coursey grabbed her by her hair and punched her multiple times in the face, the affidavit detailed. The woman stated the punching caused bruising, swelling and physical pain. The woman reportedly started to scream and Coursey placed both of his hands around her throat, restricting her airway and caused her to lose her breath. After Coursey physically assaulted her, he drove to his residence in the 10000 block of W. Bradley Drive, the affidavit stated. Coursey reportedly made the woman stay inside the residence and refused to let her leave. The woman was able to get Coursey to let her go outside where he followed her to the vehicle and sexually assaulted her, which caused physical pain, the affidavit detailed. After she was sexually assaulted, the woman reportedly went to Medical Center Hospital where she received medical treatment for her injuries and a SANE exam. Coursey was arrested, charged and transported to the Ector County Law Enforcement Center. He had two bonds totaling $50,000 and was still in custody as of Thursday afternoon, jail records show. Man charged with sexually assaulting ex-girlfriend TAGS Local News Facebook By Digital AIM Web Support – February 24, 2021 Previous article060619_OC_Employee_of_the_year_Lindsey_Bryant_JF_04Next articleBalloon campaign Digital AIM Web Support
Online candidates ‘more likely to make shortlist’On 4 Jun 2002 in Personnel Today Comments are closed. Candidates applying to the BBC through the Internet are of a higher qualitythan other applicants and are being shortlisted more often, according to thefirm’s head of online recruitment. John Clark told delegates that although the split between paper and onlineapplications was even, the corporation was shortlisting slightly morecandidates who applied via the web. “We now get around 50 per cent of our responses from the internet, andit also offersa slightly higher quality candidate than from paperapplications,” he said. He claimed online candidates tend to be more suitable because it is possibleto give more detail about job positions on the web and adverts are bigger. Clarke said the ability to attract good-quality applications at the BBC wasvital because it recruits just 6,000 to 7,000 new staff every year from morethan 100,000 applications. “It’s almost 95 per cent wastage so the BBCvalues the quality and not quantity of applications,” he said. Clarke told delegates that the BBC is advertising more in publications thathave a wide ethnic readership because it needs to improve the proportion of itsmanagers from ethnic minorities, which currently stands at only 2 per centcompared to an overall ethnic population of 8 per cent throughout theorganisation. “It means we have a lot of ethnic cleaners and caterers but not manymanagers and that’s not good enough. We want the BBC to reflect the diversityof the overall license-paying public,” he said. Related posts:No related photos. Previous Article Next Article